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METHOD FOR THE DETECTION OF ENZYMATIC ACTIVITY WIT

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专利名称:METHOD FOR THE DETECTION OF

ENZYMATIC ACTIVITY WITHMAGNETICALLY FUNCTIONALIZEDSUBSTRATES

发明人:Julian DAICH申请号:US14140499申请日:20131225

公开号:US20140162286A1公开日:20140612

摘要:The present invention provides methods for detecting an enzymatic activity, themethod including combining at least one magnetic particle to an enzyme substrate toform a magnetically modified substrate, reacting the magnetically modified substratewith at least one enzyme; and detecting a change in a magnetic property of the

magnetically modified substrate or its cleavage products, thereby detecting an activity ofsaid at least one enzyme, wherein the method may be applied to a human subject todetect a disease selected from the group consisting of rheumatitis, arthritis, an injury,Dupuytren's disease, Peyronie's disease, a collagen related disease, steatosis, fibrosis,cirrhosis, metastasis, tissue regeneration, cancer, coronary disease, a liver disease, ametabolic condition, an infection and an inflammatory disease.

申请人:Julian DAICH

地址:Toledo ES

国籍:ES

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