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专利名称：Livin-derived peptides, compositions and
uses thereof
发明人：Dina Ben-Yehuda,Yaqoub Ashhab,Boaz
Nachmias
申请号：US10559639申请日：20040531公开号：US07517949B2公开日：20090414
摘要：The present invention relates to livin-derived peptides with pro-apoptoticactivity. More specifically, the present invention provides peptides p30-Livin α and p28-Livin β, derived from Livin α and β, respectively, as well as compositions thereof. Theseherein described peptides display pro-apoptotic activity. Thus, another object of thepresent invention is the use of the peptides or compositions thereof for theenhancement and/or induction of apoptosis, as well as for the treatment of cancer.Finally, the invention also provides a method of enhancing the sensitivity of cells todeath-inducing treatments or agents through the use of the peptides of the invention.
申请人：Dina Ben-Yehuda,Yaqoub Ashhab,Boaz Nachmias
地址：Mevasseret Zion IL,Hebron IL,Ramat-Gan IL
国籍：IL,IL,IL
代理机构：Fleit Gibbons Gutman Bongini & Bianco PL
代理人：Martin Fleit,Paul D. Bianco
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